CNN1 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

Name: 钙调节蛋白-1重组兔单克隆抗体（CNN1 Recombinant Rabbit mAb）
Brand: 北京博奥森生物科技有限公司
SKU: bsm-60845R
Availability: InStock

Rrmab^?兔单抗

2026-07-01~2026-08-31，AB2607A 京东卡2026-07-01~2026-08-31，AB2607B 豪礼卡

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货号：bsm-60845R

产品详情

概述

产品编号

bsm-60845R

产品类型

重组兔单抗、mIHC精品抗体

英文名称

CNN1 Recombinant Rabbit mAb

中文名称

钙调节蛋白-1重组兔单克隆抗体

英文别名

HEL-S-14; SMCC; Sm-Calp; CN; CnnI; Calponin-1; CNN1_HUMAN; CNN1; Basic calponin; Calponin H1, smooth muscle; CNN1_MOUSE; CNN1_PIG; CNN1_RAT; calponin 1; calponin 1, basic, smooth muscle

抗体来源

Rabbit

免疫原

A synthesized peptide derived from human Calponin 1: 250-297

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Recombinant

克隆号

15E5

理论分子量

33 kDa

检测分子量

34 kDa

浓度

1mg/ml

储存液

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

研究领域

Cardiovascular > Cardiovascular Markers > Cell Markers > Smooth Muscle Cells

Cardiovascular > Vasculature > Smooth muscle cell (SMC) > Cytoskeleton

Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins

Stem Cells > Mesenchymal Stem Cells > Myogenesis

SWISS

P51911

Gene ID

1264

保存条件

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

数据库链接

Entrez Gene : 1264 Human

Entrez Gene : 484937 Dog

Entrez Gene : 12797 Mouse

Entrez Gene : 396911 Pig

Entrez Gene : 65204 Rat

Omim : 600806 Human

SwissProt : P51911 Human

SwissProt : Q08091 Mouse

SwissProt : Q08092 Pig

SwissProt : Q08290 Rat

Unigene : 465929 Human

Unigene : 4356 Mouse

Unigene : 31788 Rat

产品介绍

Calponin1是一种激动蛋白结合蛋白，是平滑肌特有的一种蛋白，可以与肌动蛋白、原肌球蛋白和钙调素结合,具有抑制平滑肌细胞收缩的功能，主要用于平滑肌肿瘤和乳腺等组织中的肌上皮细胞分布的研究。

背景资料

Predicted to enable actin binding activity. Involved in negative regulation of vascular associated smooth muscle cell proliferation. Located in cytoskeleton. [provided by Alliance of Genome Resources, Nov 2021]

基因名

CNN1

蛋白名

Calponin-1

亚基

Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1.

组织特异性

Smooth muscle, and tissues containing significant amounts of smooth muscle.

相似性

Belongs to the calponin family.
Contains 3 calponin-like repeats.
Contains 1 CH (calponin-homology) domain.

功能

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).