PIK3C3 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

bsm-61161R

重组兔单抗

PIK3C3 Recombinant Rabbit mAb

磷脂酰肌醇激酶3催化亚单位3重组兔单抗

VPS34; hVps34; 5330434F23Rik; PK3C3_HUMAN; PIK3C3; PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; 2.7.1.137; PK3C3_MOUSE; PK3C3_RAT; phosphatidylinositol 3-kinase catalytic subunit type 3; phosphoinositide-3-kinase, class 3; phosphatidylinositol 3-kinase, catalytic subunit type 3; vacuolar protein sorting 34 homolog

Rabbit

A synthesized peptide derived from human PI3 kinase p100: 800-887

IgG

Liquid

affinity purified by Protein A

Recombinant

3D8

102 kDa

105 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis.

PIK3C3

Phosphatidylinositol 3-kinase catalytic subunit type 3

Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4. Forms a complex with BECN1, PIK3R4 and either UVRAG and KIAA0226/Rubicon, or with ATG14. In this complex, presence of UVRAG and ATG14 are mutually exclusive. Part of a complex composed of PIK3R4 and PIK3CB (By similarity). Interacts with RAB7A in the presence of PIK3R4.

Midbody. Late endosome.

Ubiquitously expressed, with a highest expression in skeletal muscle.

Belongs to the PI3/PI4-kinase family.
Contains 1 C2 PI3K-type domain.
Contains 1 PI3K/PI4K domain.
Contains 1 PIK helical domain.

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.