PDIA2 Recombinant Rabbit mAb (一抗) - WB | Bioss

bsm-61394R

重组兔单抗

PDIA2 Recombinant Rabbit mAb

蛋白质二硫键异构酶重组兔单抗

I79_007873; PDA2; PDI; PDIP; PDIR; 1810041F13Rik; Pdipl; PDIA2_HUMAN; PDIA2; Pancreas-specific protein disulfide isomerase (PDIp); 5.3.4.1; PDIA2_MOUSE; protein disulfide isomerase family A member 2; protein disulfide isomerase, pancreatic; protein disulfide isomerase-associated 2; protein disulfide isomerase family A, member 2

Rabbit

A synthesized peptide derived from human PDIA2: 410-450

IgG

Liquid

affinity purified by Protein A

Recombinant

9A7

58 kDa

60 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.

PDIA2

Protein disulfide-isomerase A2

Monomer; predominantly as monomer under reducing conditions. Homodimer; disulfide-linked. Part of a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX.

Endoplasmic reticulum lumen.

Highly expressed in pancreas (at protein level).

The disulfide-linked homodimer exhibits an enhanced chaperone activity.
Glycosylated.

Belongs to the protein disulfide isomerase family.
Contains 2 thioredoxin domains.

Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.