CD166 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,IP | Bioss
Rrmab?兔单抗
货号：bsm-61678R
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概述
产品编号
bsm-61678R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
CD166 Recombinant Rabbit mAb
中文名称
活化白细胞粘附分子重组兔单抗
英文别名
CD166; MEMD; BEN; DM-GRASP; MuSC; SC1; CD166_HUMAN; ALCAM; Activated leukocyte cell adhesion molecule; CD166_MOUSE; Protein DM-GRASP; CD166_RAT; HB2; KG-CAM; Protein MEMD; SB-10 antigen; activated leucocyte cell adhesion molecule
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human ALCAM: 540-583/583
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
7E3
理论分子量
65 kDa
检测分子量
85-100 kDa
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
产品介绍
ALCAM/CD166是免疫球蛋白超家族的成员,对多种肿瘤生长和转移相关的肿瘤细胞特性具有调节作用,ALCAM/CD166在乳腺癌、前列腺癌、食道癌、结肠癌及恶性黑色素瘤等肿瘤都有一定的表达，尤以结肠、直肠癌表达显著。
背景资料
Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.
基因名
ALCAM
蛋白名
CD166 antigen
亚细胞定位
Membrane; Single-pass type I membrane protein.
组织特异性
Spleen, placenta, liver, and weakly in liver. Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells. Expressed by neurons in the brain. Restricted expression in tumor cell lines. Preferentially expressed in highly metastasizing melanoma cell lines.
相似性
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 2 Ig-like V-type (immunoglobulin-like) domains.
Contains 2 Ig-like V-type (immunoglobulin-like) domains.
功能
Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and hemophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:500-2000 | |
| IHC-P | Human, Mouse, Rat | 1:100-500 | |
| IHC-F | Human, Mouse, Rat | 1:100-500 | |
| IF | Human, Mouse, Rat | 1:100-500 | |
| Flow-Cyt | Human | Mouse, Rat | 1:50-100 |
| IP | Human, Mouse, Rat | 1:20-50 |
交叉反应
交叉反应: Human, Mouse, Rat
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