Calsequestrin Recombinant Rabbit mAb (一抗) - IHC-P,IHC-F,IF,Flow-Cyt | Bioss

bsm-61791R

重组兔单抗

Calsequestrin Recombinant Rabbit mAb

肌钙集蛋白/收钙素重组兔单抗

CASQ; CSQ1; PDIB1; VMCQA; CSQ; CSQ-1; sCSQ; CASQ1_HUMAN; CASQ1; Calmitine; Calsequestrin, skeletal muscle isoform; CASQ1_MOUSE; CASQ1_RAT; Aspartactin; Laminin-binding protein; calsequestrin 1; calsequestrin 1 (fast-twitch, skeletal muscle); calsequestrin 1, fast-twitch, skeletal muscle

Rabbit

A synthesized peptide derived from human Calsequestrin 1: 100-150/396

IgG

Liquid

affinity purified by Protein A

Recombinant

11G3

45 kDa

60 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

肌钙集蛋白，隐钙素，收钙素，是肌浆网上调控钙储存的主要结合蛋白。CASQ与内质网钙结合蛋白肌钙网蛋白具有同源性（calreticulin）。CASQ1主要在快收缩骨骼肌表达，CASQ2主要在在慢收缩骨骼肌和心肌表达。

Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. Binds 40 to 50 moles of calcium. Also binds laminin.

CASQ1

Calsequestrin-1

Sarcoplasmic reticulum lumen. Mitochondrion. Note=This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells. Also mitochondrial according to PubMed:7945294.

Belongs to the calsequestrin family.

Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. The skeletal muscle isoform (CASQ1) binds around 80 Ca(2+) ions, while the cardiac isoform (CASQ2) binds approximately 60 Ca(2+).