Glutathione synthetase Recombinant Rabbit mAb (一抗) - WB,Flow-Cyt,ICC/IF | Bioss

bsm-61855R

重组兔单抗

Glutathione synthetase Recombinant Rabbit mAb

谷胱甘肽合成酶重组兔单抗

CNSHA6; GSHS; HEL-S-64p; HEL-S-88n; GS-A/GS-B; GSH-S; GSHB_HUMAN; GSS; GSH synthetase; Glutathione synthase; 6.3.2.3; GSHB_MOUSE; GSHB_RAT; glutathione synthetase

Rabbit

A synthesized peptide derived from human GSS: 321-400

IgG

Liquid

affinity purified by Protein A

Recombinant

3H3

52 kDa

50 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Catalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner.Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in living aerobic cells and is required for numerous processes including the protection of cells against oxidative damage, amino acid transport, the detoxification of foreign compounds, the maintenance of protein sulfhydryl groups in a reduced state and acts as a cofactor for a number of enzymes.

GSS

Glutathione synthetase

Homodimer.

Cytosol

Defects in GSS are the cause of glutathione synthetase deficiency (GSS deficiency) [MIM:266130]; also known as 5-oxoprolinuria or pyroglutamic aciduria. It is a severe form characterized by an increased rate of hemolysis and defective function of the central nervous system.
Defects in GSS are the cause of glutathione synthetase deficiency of erythrocytes (GLUSYNDE)[MIM:231900]. Glutathione synthetase deficiency of erythrocytes is a mild form causing hemolytic anemia.

Belongs to the eukaryotic GSH synthase family.

Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.