FNDC5 Recombinant Rabbit mAb (一抗) | Bioss

bsm-61901R

重组兔单抗

FNDC5 Recombinant Rabbit mAb

FNDC5重组兔单抗

FRCP2; irisin; 1500001L03Rik; PeP; Pxp; FNDC5_HUMAN; FNDC5; Fibronectin type III repeat-containing protein 2; FNDC5_MOUSE; Peroxisomal protein (PeP); FNDC5_RAT; fibronectin type III domain containing 5

Rabbit

A synthesized peptide derived from human FNDC5: 50-100/212

IgG

Liquid

affinity purified by Protein A

Recombinant

5B5

24 kDa

24 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.

FNDC5

Fibronectin type III domain-containing protein 5

Cell membrane; Single-pass type I membrane protein. Peroxisome membrane; Single-pass type I membrane protein. Note=Imported in peroxisomes through the PEX5 receptor pathway.
Irisin: Secreted. Note=Detected in the blood of individuals subjected to endurance exercise.

The extracellular domain is cleaved and released from the cell membrane.
N-Glycosylated.

Contains 1 fibronectin type-III domain.

Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.