TMPRSS2 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

bsm-62174R

重组兔单抗

TMPRSS2 Recombinant Rabbit mAb

丝氨酸蛋白酶10重组兔单抗

PRSS10; D16Ertd61e; TMPS2_HUMAN; TMPRSS2; Serine protease 10; 3.4.21.122; TMPS2_MOUSE; Epitheliasin; Plasmic transmembrane protein X; transmembrane serine protease 2; transmembrane protease, serine 2

Rabbit

A synthesized peptide derived from human TMPRSS2: 1-45

IgG

Liquid

affinity purified by Protein A

Recombinant

7H2

54 kDa

52 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Plasma membrane-anchored serine protease that cleaves at arginine residues.Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate.(Microbial infection) Facilitates human coronaviruses SARS-CoV and SARS-CoV-2 infections via two independent mechanisms, proteolytic cleavage of ACE2 receptor which promotes viral uptake, and cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry.

TMPRSS2

Transmembrane protease serine 2

Cell membrane and Secreted. Activated by cleavage and secreted.

Expressed strongly in small intestine. Also expressed in prostate, colon, stomach and salivary gland.

Belongs to the peptidase S1 family.
Contains 1 LDL-receptor class A domain.
Contains 1 peptidase S1 domain.
Contains 1 SRCR domain.

Expressed strongly in small intestine. Also expressed in prostate, colon, stomach and salivary gland.