SCARB2 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,IP | Bioss

bsm-62192R

重组兔单抗

SCARB2 Recombinant Rabbit mAb

清道夫受体B2重组兔单抗

AMRF; CD36L2; EPM4; HLGP85; LGP85; LIMP-2; LIMPII; SR-BII; 9330185J12Rik; LIMP II; MLGP85; SCRB2_HUMAN; SCARB2; 85 kDa lysosomal membrane sialoglycoprotein (LGP85); CD36 antigen-like 2; Lysosome membrane protein II (LIMP II); Scavenger receptor class B member 2; LIMP2; SCRB2_MOUSE; SCRB2_RAT; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II); lysosome membrane protein 2; lysosomal integral membrane protein II

Rabbit

A synthesized peptide derived from human SCARB2: 61-100/478

IgG

Liquid

affinity purified by Protein A

Recombinant

9F3

54 kDa

80 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Acts as a lysosomal receptor for glucosylceramidase (GBA1) targeting.

SCARB2

Lysosome membrane protein 2

Interacts with GBA (via the coiled-coil domain).

Lysosome membrane; Multi-pass membrane protein.

Defects in SCARB2 are the cause of progressive myoclonic epilepsy type 4 with or without renal failure (EPM4) [MIM:254900]. An autosomal recessive progressive myoclonic epilepsy associated with renal failure in some cases. Cognitive function is preserved. Myoclonus is a brief, involuntary twitching of a muscle or a group of muscles. Cognitive function is preserved.
Note=Genetic variants in SCARB2 can act as modifier of the phenotypic expression and severity of Gaucher disease.

Belongs to the CD36 family.

Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.