ARP2; 4921510D23Rik; D6Ertd746e; ARP2_CHICK; ACTR2; Actin-like protein 2; Actin-like protein ACTL; ARP2_HUMAN; ARP2_MOUSE; ARP2_RAT; actin related protein 2; ARP2 (actin-related protein 2, yeast) homolog; ARP2 actin-related protein 2 homolog (yeast); ARP2 actin related protein 2 homolog
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Actin related protein 2: 350-387
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
11H4
理论分子量
45 kDa
检测分子量
43 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
基因名
ACTR2
蛋白名
Actin-related protein 2
亚基
Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.
亚细胞定位
Cytoplasm; cytoskeleton. Cell projection.
相似性
Belongs to the actin family. ARP2 subfamily.
功能
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament.