TAT-SF1; TATSF1; dJ196E23.2; 1600023H17Rik; 2600017A12Rik; 2700077B20Rik; RGD1563377; HTSF1_HUMAN; HTATSF1; HIV Tat-specific factor 1 (Tat-SF1); HTSF1_MOUSE; HIV Tat-specific factor 1 homolog; HIV-1 Tat specific factor 1; HIV TAT specific factor 1
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Tat SF1: 15-70/755
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
2C5
理论分子量
86 kDa
检测分子量
125 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs.
基因名
HTATSF1
蛋白名
17S U2 SnRNP complex component HTATSF1
亚细胞定位
Nuclear
功能
HIV TAT specific factor(a.k.a. HTATSF1, Tat-SF1 or HTSF1) is an 86 kDa general transcription factor that plays a role in the process of transcription elongation. However, in HIV-infected cells, this factor is up-regulated by HIV Nef and gp120 and acts as a co-factor for the Tat-enhanced transcription of the HIV virus.