Caspase 5 Recombinant Rabbit mAb (一抗) - WB | Bioss

bsm-62435R

重组兔单抗

Caspase 5 Recombinant Rabbit mAb

半胱胺酸蛋白酶蛋白5重组兔单抗

ICE(rel)III; ICEREL-III; ICH-3; CASP5_HUMAN; CASP5; CASP-5; ICE(rel)-III; Protease ICH-3; Protease TY; 3.4.22.58; ICH3; caspase 5; caspase 5, apoptosis-related cysteine protease; caspase 5, apoptosis-related cysteine peptidase

Rabbit

A synthesized peptide derived from human Caspase 5: 10-35

IgG

Liquid

affinity purified by Protein A

Recombinant

11H6

50 kDa

48 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Thiol protease that acts as a mediator of programmed cell death.Initiates pyroptosis, a programmed lytic cell death pathway through cleavage of Gasdermin-D (GSDMD): cleavage releases the N-terminal gasdermin moiety (Gasdermin-D, N-terminal) that binds to membranes and forms pores, triggering pyroptosis.

CASP5

Caspase-5

Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 10kDa (p10) subunits.

Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.

Belongs to the peptidase C14A family.
Contains 1 CARD domain.