FADS1 Recombinant Rabbit mAb (一抗) - IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss

bsm-62440R

重组兔单抗

FADS1 Recombinant Rabbit mAb

脂肪酸去饱和酶1重组兔单抗

D5D; FADS6; FADSD5; LLCDL1; TU12; 0710001O03Rik; A930006B21Rik; DSD; FADS1_HUMAN; FADS1; Delta(5) fatty acid desaturase (D5D | Delta(5) desaturase | Delta-5 desaturase); Fatty acid desaturase 1; 1.14.19.44; FADS1_MOUSE; FADS1_RAT; delta-5 desaturase; acyl-CoA (8-3)-desaturase

Rabbit

A synthesized peptide derived from human FADS1: 100-140

IgG

Liquid

affinity purified by Protein A

Recombinant

17H18

52 kDa

52 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Acts as a front-end fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 5 located between a preexisting double bond and the carboxyl end of the fatty acyl chain.

FADS1

Acyl-CoA(8-3)-desaturase

Endoplasmic reticulum membrane; Multi-pass membrane protein

Expressed in many tissues, it is most abundant in the liver, brain, adrenal gland and heart. Found as well in skeletal muscle, lung, placenta, kidney, pancreas and retina.

Belongs to the fatty acid desaturase family.
Contains 1 cytochrome b5 heme-binding domain

Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3) respectively.