IGF2BP2 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt | Bioss

Name: 胰岛素样生长因子ⅡmRNA结合蛋白2重组兔单抗（IGF2BP2 Recombinant Rabbit mAb）
Brand: 北京博奥森生物科技有限公司
SKU: bsm-62659R
Availability: InStock

KO/KD Validated Rrmab^?兔单抗

2026-07-01~2026-08-31，AB2607A 京东卡2026-07-01~2026-08-31，AB2607B 豪礼卡

一键复制说明书

货号：bsm-62659R

产品详情

概述

产品编号

bsm-62659R

产品类型

重组兔单抗、KO/KD Validated

英文名称

IGF2BP2 Recombinant Rabbit mAb

中文名称

胰岛素样生长因子ⅡmRNA结合蛋白2重组兔单抗

英文别名

IMP-2; IMP2; VICKZ2; C330012H03Rik; Neilsen; RGD1305614; IF2B2_HUMAN; IGF2BP2; IGF2 mRNA-binding protein 2; Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; VICKZ family member 2; IF2B2_MOUSE; insulin like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA binding protein 2; IGF II mRNA binding protein 2

抗体来源

Rabbit

免疫原

A synthesized peptide derived from human IGF2BP2: 500-599

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Recombinant

克隆号

2B8

理论分子量

66 kDa

检测分子量

55-62 kDa

储存液

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

研究领域

Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding

Epigenetics and Nuclear Signaling > DNA / RNA > Translation > Regulation

Immunology > Immune System Diseases > Autoimmune

Metabolism > Types of disease > Metabolic disorders

Signal Transduction > Growth Factors/Hormones > Insulin / Insulin-like

SWISS

Q9Y6M1

Gene ID

10644

保存条件

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

数据库链接

Entrez Gene : 10644 Human

Entrez Gene : 319765 Mouse

Entrez Gene : 303824 Rat

Omim : 608289 Human

SwissProt : Q9Y6M1 Human

SwissProt : Q5SF07 Mouse

Unigene : 35354 Human

Unigene : 489442 Mouse

Unigene : 17318 Rat

背景资料

RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation.Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability.

基因名

IGF2BP2

蛋白名

Insulin-like growth factor 2 mRNA-binding protein 2

亚基

Interacts with HNRPD and IGF2BP1.

亚细胞定位

Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Localizes at the connecting piece and the tail of the spermatozoa.

组织特异性

Expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia and semen (at protein level). Expressed in testicular cancer (at protein level). Expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas. Detected in fetal liver, fetal ovary, gonocytes and interstitial cells of the testis.

相似性

Belongs to the RRM IMP/VICKZ family br>Contains 4 KH domains.
Contains 2 RRM (RNA recognition motif) domains.

功能

Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs.

产品应用

应用	已检合格种属	预测种属	推荐稀释比例
WB	Human	Mouse, Rat	1:1000-2000
IHC-P	Human, Mouse, Rat		1:100-500
IHC-F	Human, Mouse, Rat		1:100-500
IF	Human, Mouse, Rat		1:100-500
Flow-Cyt	Human	Mouse, Rat	1:100-200

交叉反应

交叉反应: Human, Mouse, Rat

IGF2BP2 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt | Bioss

概述

产品应用

交叉反应

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