MAP2 (p-S136) Recombinant Rabbit mAb (一抗) - IHC-P,IHC-F,IF,ICC/IF | Bioss

Name: 磷酸化微管相关蛋白2重组兔单抗（MAP2 (p-S136) Recombinant Rabbit mAb）
Brand: 北京博奥森生物科技有限公司
SKU: bsm-62863R
Availability: InStock

Rrmab^?兔单抗

2026-07-01~2026-08-31，AB2607A 京东卡2026-07-01~2026-08-31，AB2607B 豪礼卡

一键复制说明书

货号：bsm-62863R

产品详情

概述

产品编号

bsm-62863R

产品类型

磷酸化抗体、重组兔单抗、mIHC精品抗体

英文名称

MAP2 (p-S136) Recombinant Rabbit mAb

中文名称

磷酸化微管相关蛋白2重组兔单抗

英文别名

MAP-2; MAP2A; MAP2B; MAP2C; G1-397-34; Mtap-2; Mtap2; repro4; MAP2R; MTAP2_HUMAN; MAP2; MTAP2_MOUSE; MTAP2_RAT; microtubule associated protein 2; MAP2 (phospho-S136); p-MAP2; phospho-MAP2; MAP2 (phospho-Ser136)

抗体来源

Rabbit

免疫原

A synthesized peptide derived from human MAP2 around the phosphorylation site of S136: NLPP-pS-PPP(全长1827aa)

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Recombinant

克隆号

19F17

理论分子量

200 kDa

检测分子量

70,280 kDa

储存液

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

SWISS

P11137

Gene ID

4133

保存条件

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

数据库链接

Entrez Gene : 4133 Human

Entrez Gene : 17756 Mouse

Entrez Gene : 25595 Rat

Omim : 157130 Human

SwissProt : P11137 Human

SwissProt : P20357 Mouse

SwissProt : P15146 Rat

Unigene : 368281 Human

Unigene : 256966 Mouse

Unigene : 10484 Rat

产品介绍

微管相关蛋白 2（MAP-2)是一种磷蛋白质，在正常脑组织中，主要存在于神经元的胞体、树突和树突棘，是脑内最丰富的蛋白之一。MAP-2在其调节微管的聚合作用和微管的稳定性以及对神经元轴突和树突的发生、延长、稳定和突触可塑性调节具有重要作用。

背景资料

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

基因名

Map2

蛋白名

Microtubule-associated protein 2

亚细胞定位

Cytoplasm, cytoskeleton (Probable).

翻译后修饰

Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). MAP2A/c is phosphorylated. Isoform MAP2c is phosphorylated by FYN at Tyr-67.

相似性

Contains 3 Tau/MAP repeats.

功能

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.