LC3A Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,ICC/IF,IP | Bioss

Rrmab?兔单抗
2026-07-01~2026-08-31,AB2607A 京东卡2026-07-01~2026-08-31,AB2607B 豪礼卡
货号:bsm-62899R
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概述

产品编号
bsm-62899R
产品类型
重组兔单抗
英文名称
LC3A Recombinant Rabbit mAb
中文名称
自噬微管相关蛋白轻链3重组兔单抗
英文别名
ATG8E; LC3; LC3A; MAP1ALC3; MAP1BLC3; 1010001H21Rik; 4922501H04Rik; LC3-I; LC3-II; MLP3A_HUMAN; MAP1LC3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; Microtubule-associated proteins 1A/1B light chain 3A (MAP1A/MAP1B LC3 A | MAP1A/MAP1B light chain 3 A); MLP3A_MOUSE; MLP3A_RAT; microtubule associated protein 1 light chain 3 alpha
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human LC3A: 84-121
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
7F11
理论分子量
14 kDa
检测分子量
17 kDa
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles .While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
基因名
MAP1LC3A
蛋白名
Microtubule-associated proteins 1A/1B light chain 3A
亚基

3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. Interacts with SQSTM1. Interacts with TP53INP1 and TP53INP2

亚细胞定位

Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome. Note=LC3-II binds to the autophagic membranes.

组织特异性

Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.

翻译后修饰

The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.

相似性

Detects a band of approximately 16 kDa (predicted molecular weight: 14 kDa).

功能

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) 

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产品应用

应用 已检合格种属 预测种属 推荐稀释比例
WB Human, Mouse, Rat Pig 1:1000-5000
IHC-P Human, Mouse, Rat Pig 1:100-500
IHC-F Human, Mouse, Rat Pig 1:100-500
IF Human, Mouse, Rat Pig 1:100-500
ICC/IF Human Mouse, Rat, Pig 1:50-200
IP Human, Mouse, Rat, Pig 1:20-50

交叉反应

交叉反应: Human, Mouse, Rat (predicted: Pig)

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