ID1 Recombinant Rabbit mAb (一抗) - IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss

bsm-54101R

重组兔单抗

ID1 Recombinant Rabbit mAb

DNA结合抑制因子1重组兔单抗

ID; bHLHb24; D2Wsu140e; Idb1; ID125A; ID1_HUMAN; ID1; Class B basic helix-loop-helix protein 24 (bHLHb24); Inhibitor of DNA binding 1; Inhibitor of differentiation 1; ID1_MOUSE; Id-1; ID1_RAT; inhibitor of DNA binding 1, dominant negative helix-loop-helix protein; DNA-binding protein inhibitor ID-1

Rabbit

Recombinant human ID1 protein

IgG

Liquid

affinity purified by Protein A

Recombinant

5F1

16 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

ID proteins contain a helix-loop-helix (HLH) motif and regulate tissue-specific transcription within several cell lineages. They do not bind DNA directly, but inhibit lineage commitment by binding basic helix-loop-helix (bHLH) transcription factors through their HLH motif. ID proteins contribute to cell growth, senescence, differentiation and angiogenesis. Id1 mRNA is highly expressed in heart, lung and kidney and has lower expression in brain and liver. Two transcript variants encoding different isoforms have been found for this gene.

ID1

DNA-binding protein inhibitor ID-1

Heterodimer with other HLH proteins. Interacts with COPS5.

Cytoplasm. Nucleus.

Contains 1 bHLH (basic helix-loop-helix) domain.

ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding.