YBX3 | CSDA/DBPA Rabbit pAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

bs-12985R

宠物抗体、农牧业/家禽抗体

YBX3 | CSDA/DBPA Rabbit pAb

冷休克蛋白DBPA抗体

CSDA; CSDA1; DBPA; ZONAB; Dpba; MSY3; MSY4; Yb2; oxyR; YBOX3_HUMAN; YBX3; Cold shock domain-containing protein A; DNA-binding protein A; Single-strand DNA-binding protein NF-GMB; Q61478_MOUSE; Q68G78_MOUSE; Q8BPG0_MOUSE; YBOX3_MOUSE; Y-box protein 3; Q3KRC7_RAT; YBOX3_RAT; Muscle Y-box protein YB2; RYB-A; Y-box-binding protein A; Y-box binding protein 3; cold shock domain protein A; cold-shock domain containing A1

Rabbit

KLH conjugated synthetic peptide derived from human DBPA/CSDA1: 165-270/372

IgG

Liquid

affinity purified by Protein A

Polyclonal

40 kDa

40 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CSDA is a 372 amino acid nuclear and cytoplasmic protein that is highly expressed in skeletal muscle and heart. Containing one CSD (cold-shock) domain, CSDA is thought to bind to GM-CSF promoter, full length mRNA and to short RNA sequences containing a specific consensus site. CSDA is suggested to have a role in translation repression and is found in a mRNP complex with MSY2. MSY2 belongs to the Y-box family of multifunctional proteins that regulate both transcription and translation. CSDA participates in promoting cell proliferation and expression of cyclin D1 and proliferating cell nuclear antigen (PCNA). CSDA is regarded to be an important component of the mechanisms that sense epithelial density and in regulating the switch between proliferation and differentiation through complex transcriptional networks.

YBX3

Y-box-binding protein 3

Cytoplasm. Nucleus.

Highly expressed in skeletal muscle and heart.

Contains 1 CSD (cold-shock) domain.

Binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression.