CD63 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,ICC/IF | Bioss

Name: 黑色素瘤相关抗原重组兔单抗（CD63 Recombinant Rabbit mAb）
Brand: 北京博奥森生物科技有限公司
SKU: bsm-52384R
Availability: InStock

Rrmab^?兔单抗

2026-07-01~2026-08-31，AB2607A 京东卡2026-07-01~2026-08-31，AB2607B 豪礼卡

一键复制说明书文献引用(5)

货号：bsm-52384R

产品详情

概述

产品编号

bsm-52384R

产品类型

重组兔单抗、mIHC精品抗体

英文名称

CD63 Recombinant Rabbit mAb

中文名称

黑色素瘤相关抗原重组兔单抗

英文别名

AD1; HOP-26; ME491; MLA1; OMA81H; Pltgp40; TSPAN30; CD63_HUMAN; CD63; Granulophysin; Lysosomal-associated membrane protein 3 (LAMP-3); Lysosome integral membrane protein 1 (Limp1); Melanoma-associated antigen ME491; Ocular melanoma-associated antigen; Tetraspanin-30 (Tspan-30); CD63 molecule; CD63 antigen (melanoma 1 antigen); AD1 antigen

抗体来源

Rabbit

免疫原

A synthesized peptide derived from human CD63: 100-200

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Recombinant

克隆号

4C2

理论分子量

26 kDa

检测分子量

30-60 kDa

储存液

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

研究领域

Cancer > Invasion/microenvironment > ECM > Cell adhesion

Cancer > Tumor biomarkers > Tumor antigens

Cardiovascular > Blood > Platelets

Immunology > Cell Type Markers > CD > Platelets

Tags & Cell Markers > Cell Type Markers > Tumor Associated

SWISS

P08962

Gene ID

967

保存条件

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

数据库链接

Entrez Gene : 967 Human

SwissProt : P08962 Human

产品介绍

CD63为溶酶体膜糖蛋白也是一种细胞表面糖蛋白，可表达在多种细胞的表面和胞浆内，血小板活化后即转移至膜表面。
CD63—又称黑色素瘤相关抗原MLA1和整合素形成复合物。是血液血小板活化的标志。与一些肿瘤的进展也有关联。

背景资料

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]

基因名

CD63

蛋白名

CD63 antigen

亚细胞定位

Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Note=Also found in Weibel-Palade bodies of endothelial cells. Located in platelet dense granules.

组织特异性

Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.

相似性

Belongs to the tetraspanin (TM4SF) family.

功能

This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation.