MAP1LC3A | LC3A Mouse mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

Name: 自噬微管相关蛋白轻链3单克隆抗体（MAP1LC3A | LC3A Mouse mAb）
Brand: 北京博奥森生物科技有限公司
SKU: bsm-33309M
Availability: InStock

AB2609A 京东卡组化荧光优选(赠品)

一键复制说明书文献引用(4)

货号：bsm-33309M

产品详情

概述

产品编号

bsm-33309M

产品类型

mIHC精品抗体

英文名称

MAP1LC3A | LC3A Mouse mAb

中文名称

自噬微管相关蛋白轻链3单克隆抗体

英文别名

ATG8E; LC3; LC3A; MAP1ALC3; MAP1BLC3; 1010001H21Rik; 4922501H04Rik; LC3-I; LC3-II; MLP3A_HUMAN; MAP1LC3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; Microtubule-associated proteins 1A/1B light chain 3A (MAP1A/MAP1B LC3 A | MAP1A/MAP1B light chain 3 A); MLP3A_MOUSE; MLP3A_RAT; microtubule associated protein 1 light chain 3 alpha

抗体来源

Mouse

免疫原

KLH conjugated synthetic peptide derived from human LC3A: 1-100/121

亚型

IgG

性状

Size : 50ul/100ul/200ul
Liquid

Size : 200ug (PBS only)
Lyophilized
Note: Centrifuge tubes before opening. Reconstitute the lyophilized product in distilled water. Optimal concentration should be determined by the end user.

纯化方法

affinity purified by Protein G

克隆类型

Monoclonal

克隆号

7G10

理论分子量

14/16 kDa

检测分子量

14 kDa

浓度

1mg/ml

储存液

Size : 50ul/100ul/200ul
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Size : 200ug (PBS only)
0.01M PBS (pH7.4).

SWISS

Q9H492

Gene ID

84557

保存条件

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

数据库链接

Entrez Gene : 84557 Human

Entrez Gene : 66734 Mouse

Entrez Gene : 362245 Rat

Omim : 601242 Human

SwissProt : Q9H492 Human

SwissProt : Q91VR7 Mouse

SwissProt : Q6XVN8 Rat

Unigene : 632273 Human

Unigene : 196239 Mouse

Unigene : 3135 Rat

基因名

MAP1LC3A

蛋白名

Microtubule-associated proteins 1A/1B light chain 3A

亚基

3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. Interacts with SQSTM1. Interacts with TP53INP1 and TP53INP2

亚细胞定位

Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome. Note=LC3-II binds to the autophagic membranes.

组织特异性

Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.

翻译后修饰

The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.

相似性

Detects a band of approximately 16 kDa (predicted molecular weight: 14 kDa).

功能

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes)