MARK3 | cTAK1 Recombinant Rabbit mAb (一抗) - WB,Flow-Cyt | Bioss

bsm-54462R

重组兔单抗

MARK3 | cTAK1 Recombinant Rabbit mAb

兔抗磷酸化丝氨酸/苏氨酸蛋白激酶MARK3单克隆抗体

CTAK1; KP78; PAR1A; Par-1a; VIPB; 1600015G02Rik; A430080F22Rik; C-TAK1; ETK-1; ETK1; Emk2; MPK10; MARK3_HUMAN; MARK3; C-TAK1 (cTAK1); Cdc25C-associated protein kinase 1; ELKL motif kinase 2 (EMK-2); Protein kinase STK10; Ser/Thr protein kinase PAR-1 (Par-1a); Serine/threonine-protein kinase p78; 2.7.11.1; MARK3_MOUSE; MPK-10; MARK3_RAT; microtubule affinity regulating kinase 3; MAP/microtubule affinity-regulating kinase 3

Rabbit

Recombinant human MARK3 protein: 600-750

IgG

Liquid

affinity purified by Protein A

Recombinant

2F7

84 kDa

84 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

MARK3

MAP/microtubule affinity-regulating kinase 3

Ubiquitous.

Belongs to the protein kinase superfamily.
CAMK Ser/Thr protein kinase family. MARK subfamily.
Contains 1 KA1 (kinase-associated) domain.
Contains 1 protein kinase domain.
Contains 1 UBA domain.

Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.