CD9 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

bsm-52264R

重组兔单抗

CD9 Recombinant Rabbit mAb

CD9重组兔单抗

BTCC-1; DRAP-27; MIC3; MRP-1; TSPAN-29; TSPAN29; CD9_HUMAN; CD9; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein (MRP-1); Tetraspanin-29 (Tspan-29); p24; CD9_MOUSE; CD9_RAT; CD9 molecule; CD9 antigen (p24); motility related protein-1; Tetraspanin-29

Rabbit

A synthesized peptide derived from human CD9: 200-228

IgG

Liquid

affinity purified by Protein A

Recombinant

4C2

25 kDa

24 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD9是一种普遍存在于细胞膜表面属于四跨膜超蛋白家族的细胞表面糖蛋白, 参与质膜的融合过程，在细胞膜生物学中发挥重要作用。
近年来经研究发现，CD9与多种肿瘤转移有关，故称肿瘤转移抑制基因亦称抗肿瘤转移基因。是一个新的肿瘤转移抑制基因膜运动相关蛋白-1(CD9/MRP-1)，其分子功能还有待于进一步研究。CD9主要在早B细胞、活化T淋巴细胞、嗜酸性粒细胞、嗜碱性粒细胞和血小板表达。

This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]

CD9

CD9 antigen

Forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers with other members of the tetraspanin family. Associates with CR2/CD21 and with PTGFRN/CD9P1. Interacts directly with IGSF8.

Membrane; Multi-pass membrane protein.

Expressed by a variety of hematopoietic and epithelial cells.

Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids.

Belongs to the tetraspanin (TM4SF) family.

Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion.