IL-8 Recombinant Rabbit mAb (一抗) - IHC-P | Bioss

bsm-63266R

重组兔单抗

IL-8 Recombinant Rabbit mAb

白介素8重组兔单抗

GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8; AMCF-I; IL8_HUMAN; CXCL8; IL-8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1 (GCP-1); Monocyte-derived neutrophil chemotactic factor (MDNCF); Monocyte-derived neutrophil-activating peptide (MONAP); Neutrophil-activating protein 1 (NAP-1); Protein 3-10C; T-cell chemotactic factor; IL8_PIG; Alveolar macrophage chemotactic factor I (AMCF-I); C-X-C motif chemokine ligand 8; interleukin 8; neutrophil-activating peptide 1; granulocyte chemotactic protein 1; monocyte-derived neutrophil chemotactic factor; lung giant cell carcinoma-derived chemotactic protein; tumor necrosis factor-induced gene 1; monocyte-derived neutrophil-activating peptide; lymphocyte derived neutrophil activating peptide; beta endothelial cell-derived neutrophil activating peptide; alveolar macrophage chemotactic factor I

Rabbit

A synthesized peptide derived from human IL 8: 1-99

IgG

Liquid

affinity purified by Protein A

Recombinant

3F10

11 kDa

11 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

白介素-8

Chemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection. Also plays an important role in neutrophil activation. Released in response to an inflammatory stimulus, exerts its effect by binding to the G-protein-coupled receptors CXCR1 and CXCR2, primarily found in neutrophils, monocytes and endothelial cells.

CXCL8

Interleukin-8

Homodimer.

Secreted.

Several N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. In general, IL-8(1-77) is referred to as interleukin-8. IL-8(6-77) is the most promiment form.

Belongs to the intercrine alpha (chemokine CxC) family.

IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.