SERPINB3 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

bsm-43190R

重组兔单抗

SERPINB3 Recombinant Rabbit mAb

丝氨酸蛋白酶抑制剂B3重组兔单抗

HsT1196; SCC; SCCA-1; SCCA-PD; SCCA1; SSCA1; T4-A; SPB3_HUMAN; SERPINB3; Protein T4-A; Squamous cell carcinoma antigen 1 (SCCA-1); SCCA; serpin family B member 3; squamous cell carcinoma antigen 1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 3

Rabbit

Recombinant human SERPINB3 protein: 1-390/390

IgG

Liquid

affinity purified by Protein A

Recombinant

8C9

45 kDa

45 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma.

SERPINB3

Serpin B3

Cytoplasm. Seems to also be secreted in plasma by cancerous cells but at a low level.

Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).

Belongs to the serpin family. Ov-serpin subfamily.

May act as a protease inhibitor to modulate the host immune response against tumor cells.