CHRM4 Rabbit pAb (一抗) | Bioss
货号：bs-20372R
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概述
产品编号
bs-20372R
英文名称
CHRM4 Rabbit pAb
中文名称
毒蕈碱型乙酰胆碱受体M4抗体
英文别名
HM4; M4R; AChR M4; Chrm-4; M4; mm4 mAChR; ACM4_HUMAN; CHRM4; ACM4_MOUSE; ACM4_RAT; cholinergic receptor muscarinic 4; acetylcholine receptor, muscarinic 4
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human CHRM4: 131-230/479 <Extracellular>
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
53 kDa
检测分子量
55 kDa
浓度
1mg/ml
储存液
Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse, Rat | 1:500-2000 |
交叉反应
交叉反应: Human (predicted: Mouse, Rat)
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靶标
基因名
CHRM4
蛋白名
Muscarinic acetylcholine receptor M4
亚细胞定位
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
相似性
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM4 sub-subfamily.
功能
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and postassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus.
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