FosB Recombinant Rabbit mAb (一抗) - WB,ICC/IF | Bioss

bsm-52071R

重组兔单抗

FosB Recombinant Rabbit mAb

FosB重组兔单抗

AP-1; G0S3; GOS3; GOSB; fra-2; FOSB_HUMAN; FOSB; FosB proto-oncogene, AP-1 transcription factor subunit; G0/G1 switch regulatory protein 3; Transcription factor AP-1 subunit FosB; FBJ murine osteosarcoma viral oncogene homolog B; oncogene FOS-B; activator protein 1

Rabbit

A synthesized peptide derived from human FOSB: 1-150/338

IgG

Liquid

affinity purified by Protein A

Recombinant

9C11

36 kDa

38 FosB2,48 FosB. kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

转录调节因子（Transcriptin Regulators）
FOS B属于转录因子AP-1家族;FosB是一种转录因子，表达后能在脑内维持数周甚至几个月。长期药物滥用能引起伏核内FosB表达稳定地增加，表明FosB的表达可能是药物成瘾的分子转换机制，是当今药物成瘾研究中最受重视的转录因子。

Cellular oncogenes, or proto-oncogenes, play pivotal roles in cellular communication pathways that regulate normal growth, development and differentiation. The cellular oncogene families fos and jun encode nuclear proteins that can function as transcription factors. The fos family of nuclear oncogenes encode cFos, Fos B, (fos-related antigen) Fra 1, and Fra 2. Also named as DKFZp686C0818; FBJ murine osteosarcoma viral oncogene homolog B; FosB; G0/G1 switch regulatory protein 3; G0S3; GOS3; GOSB; MGC42291; Oncogene FOS B; Protein fosB.

FOSB

Protein FosB

Heterodimer.

Nucleus.

Belongs to the bZIP family. Fos subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.

FosB interacts with Jun proteins enhancing their DNA binding activity.