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神经疾病相关抗体大全-北京博奥森生物技术有限公司
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神经疾病相关抗体大全
发表者:北京博奥森生物      发表时间:2021-9-9


神经退行性疾病是一类特定亚型神经元进行性丢失导致功能障碍的疾病,主要包括阿尔茨海默病、帕金森病、多发性硬化症、肌萎缩侧索硬化症和共济失调等疾病。目前这类疾病患者正在不断增多,但能早期诊治的患者比例少之又少,而利用神经疾病相关抗体有助于对该疾病做进一步研究,同时也有助于临床的早期诊断和治疗。

抗体介绍

HSP70是一类分子伴侣,可以调控Tau、α-突触核蛋白、TDP-43、朊蛋白和多聚谷氨酰胺蛋白的代谢进程,抑制神经退行性疾病中错误折叠蛋白质的聚集和毒性作用。

文献引用:(12篇)

Preparation of photothermal responsive and ROS generative gold nanocages for cancer therapy.

Chemical Engineering Journal.

DOI: 10.1016/j.cej.2021.129744





文献引用:(31篇)

Osteoclast-derived apoptotic bodies couple bone resorption and formation in bone remodeling.

Bone Research.

PMID: 33431863





抗体介绍

Beclin-1是自噬中的重要角色,阿尔兹海默症早期,Beclin-1在脑部病变区域中的表达是呈下降趋势的,,研究表明该蛋白的表达会减少细胞内外的淀粉样病变,而表达减少则会增加神经元内淀粉样蛋白的聚集。因此,增加beclin-1水平可能成为潜在的AD的治疗方案。

文献引用:(20篇)

Far-infrared protects vascular endothelial cells from advanced glycation end products-induced injury via PLZF-mediated autophagy in diabetic mice.

Scientific Reports.

PMID: 28071754





文献引用:(47篇)

RBM39 Alters Phosphorylation of c-Jun and Binds to Viral RNA to Promote PRRSV Proliferation.

Frontiers in Immunology.

PMID: 34079549






文献引用:(13篇)

Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression.

Molecular Therapy-Nucleic Acids.

PMID: 32781430





文献引用:(3篇)

CDC42EP3 is a key promoter involved in the development and progression of gastric cancer.

Carcinogenesis.

PMID: 34111280





文献引用:(1篇)

Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation,and Nrf2 activation in a toxic model combining hyperglycemia+Aβ1-42 peptide in rat hippocampal neurons.

Neurochemistry International.

PMID: 32781098





文献引用:(1篇)

Aqueous extract from You-Gui-Yin ameliorates cognitive impairment of chronic renal failure micethrough targeting hippocampal CaMKIIα/CREB/BDNF and EPO/EPOR pathways.

J Ethnopharmacol.

PMID: 31055001





文献引用:(5篇)

Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain.

J Neuroinflammation.

PMID: 30975172













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